Enter your departure date, select your vaccines, and get exact dose-by-dose appointment dates — with warnings if you're running short on time.
1. Set your departure date — the date you leave for your international destination.
2. Select each vaccine you need (your travel clinic or CDC destination pages can advise which ones).
3. For multi-option vaccines (like Hepatitis B or Typhoid), choose the standard or accelerated schedule variant.
4. Read your appointment table — each dose shows its exact recommended date, days before departure, and a green/amber/red status.
5. Print or download the schedule to bring to your clinic.
A red date means that dose falls after your departure — you will not complete protection in time on that schedule. Switch to an accelerated schedule if one is available, or consult a travel health provider about partial protection options.
The CDC recommends booking a travel health appointment at least 4–6 weeks before departure, and ideally 8–12 weeks for multi-dose series. The absolute latest you can start depends on the vaccine: Yellow Fever needs just 10 days; standard Hepatitis B takes 6 months. The calculator's "earliest start date to complete series" shows the minimum date to begin each vaccine for full protection.
A two-dose injectable series (e.g., Havrix, Vaqta) given at least 6 months apart. The first dose provides substantial protection — good enough for most short trips — within about 2 weeks. Get Dose 1 at least 2 weeks before departure; Dose 2 follows 6 months later per routine schedule.
Standard series (Engerix-B, Recombivax HB): 0, 1, and 6 months. Full protection requires 6+ months of lead time. Heplisav-B (adults ≥18) is an accelerated 2-dose series given 28 days apart, requiring about 6 weeks total. The combination Twinrix (Hep A + B) has an accelerated schedule of days 0, 7, and 21–30 plus a 12-month booster.
Injectable Vi polysaccharide (Typhim Vi): single dose ≥2 weeks before travel, booster every 2 years. Oral Vivotif: 4 capsules on alternate days (days 1, 3, 5, 7); last dose ≥7 days before departure; booster every 5 years.
Single lifetime dose for most travelers. The International Certificate of Vaccination (Yellow Card) becomes valid exactly 10 days after immunization. Required for entry into many African and South American countries and mandatory if arriving from a yellow-fever-endemic country.
Two doses: standard interval 28 days; adults ≥18 may use the accelerated 7-day interval. Last dose must be given ≥7 days before departure. A booster may be given ≥1 year after the initial series.
Updated by ACIP in 2021 from 3 doses to 2 doses on days 0 and 7. Recommended for travelers to remote areas, adventure travelers, long-stay travelers to endemic countries, and those with risk of animal exposure where post-exposure care is unavailable.
Single dose ≥10 days before travel. Required for all travelers to Saudi Arabia for Hajj or Umrah. Recommended for travelers to the meningitis belt of sub-Saharan Africa, especially December–June.
Single oral dose ≥10 days before travel for adults 18–64. Provides protection for about 3 months. Recommended for travelers to high-risk areas with limited access to safe water.
Two-dose series ≥28 days apart. Most adults born before 1957 are considered immune. Travelers with documented 2-dose MMR history are covered. If unvaccinated, start at least 6 weeks before departure to complete both doses in time.
Single annual dose. Allow at least 2 weeks for protection to develop. Particularly important for travelers to tropical regions (year-round flu) or the Southern Hemisphere during its flu season (April–September).
Single booster dose. Recommended if not vaccinated within 10 years, or within 5 years for high-risk travelers. Allow 2 weeks for full protection.
The CDC recommends visiting a travel health provider at least 4–6 weeks before departure, and ideally 8–12 weeks for multi-dose series like Hepatitis B or Rabies PrEP. Some vaccines like Yellow Fever need only 10 days, but multi-dose series can take 6 months (standard Hepatitis B).
The Yellow Card (ICVP) becomes valid exactly 10 days after vaccination. Countries that require proof will not accept a certificate issued fewer than 10 days before arrival. Get vaccinated at an authorized yellow fever vaccination center — not all clinics are authorized to issue valid certificates.
Most inactivated travel vaccines can be given at the same visit with no increased side effects. However, two or more live vaccines (MMR, Varicella, Yellow Fever) should be given on the same day or at least 28 days apart. Your travel health provider will sequence appointments accordingly.
Heplisav-B (adults ≥18) is a 2-dose series just 28 days apart, requiring about 6 weeks total lead time. The combination Twinrix (Hep A + B) has an accelerated schedule: doses on days 0, 7, and 21–30 plus a 12-month booster, fitting within one month. Standard Engerix-B requires 0, 1, and 6 months.
Since 2021, ACIP updated the recommendation to 2 doses on days 0 and 7. This is faster and less expensive than the old 3-dose regimen. Travelers with sustained risk beyond 3 years may need a booster dose or antibody titer check. Always consult your travel health provider.
Injectable (Typhim Vi): single shot ≥2 weeks before departure, booster every 2 years. Oral (Vivotif): 4 capsules on alternate days, last dose ≥7 days before travel, booster every 5 years. Both are refrigerator-stable and roughly equal in efficacy. The oral vaccine cannot be taken with antibiotics.